Regulatable growth of filamentous fungi

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S004000, C435S006120, C435S041000, C435S069100, C435S183000, C435S252300, C435S320100, C435S254100, C435S254300, C435S254400, C536S023200, C536S023400, C536S023700, C536S023740, C530S350000

Reexamination Certificate

active

06936449

ABSTRACT:
The present invention generally relates to hyphal growth in fungi and in particular describes the modulation of genes associated with hyphal growth in filamentous fungi. The present invention provides methods and systems for the production of proteins and/or chemicals from filamentous fungi which comprise modulation of genes associated with hyphal growth. Specifically, the present invention is directed to a full length cotA gene, its gene product and methods of use.

REFERENCES:
patent: 4816567 (1989-03-01), Cabilly et al.
Buhr et al. (Mol. Gen. Genet., 1996, vol. 251:565-572).
Yarden et al. (EMBO J., 1992, vol. 11:2159-2166).
Altschul, Stephen F., et al., “Basic Local Alignment Search Tool”, Academic Press Limited, pp. 403-410, 1990.
Altschul, Stephen F., et al., “Gapped BLAST and PSI-BLAST : a new generation of protein database search programs,” Nucleic Acids Research, vol. 25, No. 17, pp. 3389-3402, 1997.
Carter, Paul et al., “Improved oligonucleotide site-directed mutagenesis using M13 vectors,” Nucleic Acids Research, vol. 13, No. 12, pp. 4431-4443, 1985.
Collinge, Annette J. et al., “Physiology and Cytology of Septation and Branching in a Temperature-Sensitive Colonial Mutant, (cot 1 ) ofNeurospora crassa” Trans. Br. mycol. Soc., 71 (1) pp. 107-120, 1978.
Deutscher Murray P., “Rethinking Your Purification Procedure,” Methods in Enzymology, vol. 182, pp 779-780, 1990.
Gorovist, Rena et al., “A Mutation within the Catalytic Domain of COT1 Kinase Confers Changes in the Presence of Two COT 1 Isoforms and in Ser/Thr Protein Kinase and Phosphatase Activities inNeurospora crassa,” Fungal Genetics and Biology, Academic Press, vol. 27, pp. 264-274, 1999.
Kohler, G., et al. “Continuous cultures of fused cells secreting antibody of predefined specificity,” Nature, vol. 256, pp. 495-497, Aug. 7, 1975.
Murray, Elizabeth E. et al., “Codon usage in plant genes<” Nucleic Acids Research, , vol. 17, No. 2, pp. 477-498, 1989.
*Scopes, Protein Purification : Principles and Practice, Springer-Verlag, New York, New York, 1982.
Steele, Graham C. et al., “Effect of Temperature and Temperature Shifts on Growth and Branching of a Wild Type and a Temperature Sensitive Colonial Mutant (Cot1) ofNeurospora crassa,” Archives of Microbiology, vol. 113, pp. 43-48, 1977.
Ward, Michael et al., “Use ofAspergillusoverproducing mutants, cured for integrated plasmid, to overproduce heterologous proteins,” Applied Microbiology and Biotechnology, vol. 39, pp. 738-743, Springer-Verlag, 1993.
Wells, J.A., et al., “Importance of hydrogen-bond formation in stabilizing the transition state of subtilisin,” Phil. Trans. R. Soc. Lond., 317, pp. 415-423, 1986.
Yarden, Oded et al., “cot-1, a gene required for hphal elongation inNeurospora crassa, encodes a protein kinase,” The EMBO Journal, vol. 11, No. 6, pp. 2159-2166, 1992.
Zoller, Mark J. et al., “Oligonucleotide-directed mutagenesis using M13-derived vectors : an efficient and general procedure for the production of point mutations in any fragment of DNA,” Nucleic Acids Research, vol. 10, No. 20, pp. 6487-6500, 1982.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Regulatable growth of filamentous fungi does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Regulatable growth of filamentous fungi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Regulatable growth of filamentous fungi will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3501866

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.