Regioselective nitration of aromatic compounds and the reaction

Details Regioselective nitration of aromatic compounds and the reaction Regioselective nitration of aromatic compounds and the reaction

1998-08-07

1999-08-31

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568936, C07C20500

Patent

active

059466383

ABSTRACT:
A method is described for the regioselective nitration of substituted aromatic compounds. The reaction is effected by heating the aromatic compound to a temperature within the range of 70-90.degree. C. in the presence of a solid zeolite catalyst and adding concentrated nitric acid to the heated mixture, the concentration of the acid ranging from 90-98%, by weight.

REFERENCES:
Kwok J. Thmas et al. J. Org. Chem. 1994, 59, 4939-4942.
Smith Keith et al. Chem. Commun. Cambridge, 1996, 4, 469-470.
Gaudreault J. et al. Journal of Parmaceutical Science, 1988, 77 (2), 185-187.
Japanese Abstract (JP 51019734 A) WPIDS data base, Jan. 09, 1993.

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