Regioselective enzymatic deacylation of sucrose esters in anhydr

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435196, 435197, 435198, 435219, C12P 1912

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054459516

ABSTRACT:
A process for the preparation of partially acylated derivatives of sucrose by the enzyme catalyzed deacylation of sucrose esters, wherein said process comprises treating a sucrose ester selected from the group consisting of sucrose octaacylate, sucrose heptaacylate, and sucrose hexaacylate in an anhydrous organic medium, with an enzyme or combination of enzymes capable of catalyzing the deacylation of said sucrose ester to produce a partially deacylated sucrose derivative having free hydroxyl group(s) in pre-selected position(s), and recovering the resulting partially deacylated sucrose derivative.

REFERENCES:
patent: 5141860 (1992-08-01), Bornemann et al.
Ong et al., Preparation of 2,3,6,3',4'-penta-o-acetyl Sucrose, The Precursor of Sucralose, by Enzymatic Methods, Biorganic & Medicinal Chemistry Letters, vol. 2, No. 2, pp. 161-164, 1992.
Chang et al., J. Carbohydrate Chemistry, 10(2), 251-261 (1991).
Chang et al., Carbohydrate Research, 222, 121-129 (1991).
Kloosterman et al., J. Carbohydrate Chemistry, 8(5), 693-704 (1989).
Ong et al., Bioorganic & Medicinal Chemistry Letters, 2(2), 161-164 (1992).
J. S. Dordick, "Designing Enzymes for Use in Organic Solvents", Biotechnol. Prog., 1992, No. 8, 259-267.
A. M. Klibanov, in "Enzymes that work in organic solvents", Chemtech, Jun. 1986, 354-359.
H. M. Sweers et al., J. Am. Chem. Soc., 108, 6421 (1986).
W. J. Hennen et al., J. Org. Chem., 53, 4939 (1988).
J. Zemek et al., Coll. Czech. Chem. Commun., 53, 1851 (1988).
A. Ballesteros et al., Tetrahedron, 45, 7077 (1989).
S. Tomic et al., Carbohydrate Res., 210, 191 (1991).
K. Kefurt et al., Carbohydrate Res., 223, 137 (1992).

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