Regionless multiple label scintillation counting

Details Regionless multiple label scintillation counting Regionless multiple label scintillation counting

1985-04-08

1986-12-09

Church, Craig E.

Radiant energy

Invisible radiant energy responsive electric signalling

With or including a luminophor

250364, 250328, G01T 120

Patent

active

046282050

ABSTRACT:
Apparatus and a regionless method of ascertaining the activity of each radionuclide in a dual-label sample. A set of correlation curves is generated utilizing quench standards for both a low energy radionuclide and a high energy radionuclide. A test sample was then counted and the quench-indicating parameters for the test sample are compared with the quench-indicating parameters of the correlation curves to determine the appropriate contribution of each radionuclide to the overall energy spectra of the test sample. From this comparison the overall count rate for the test sample may be allocated between a low energy radionuclide and a high energy radionuclide. By dividing the count rates by efficiencies determined from another set of correlation curves the actual disintegration per minute (DPM) rate for each radionuclide may be ascertained.

REFERENCES:
patent: 3715584 (1973-02-01), Rosenstingl
patent: 4029401 (1977-06-01), Nather
patent: 4085325 (1978-04-01), Atallah et al.
patent: 4555629 (1985-11-01), Everett et al.
The Tri-Carb 460C Automatic Liquid Scintillation System by Packard Operation Manual, Section 3, 1980, pp. 3-1 to 3-20.
Kobayashi, Y. and D. V. Maudsley, Practical Aspects of Double Isotope Counting, pp. 76-85.
Bush, Elizabeth T., Liquid Scintillation Counting of Doubly-Labelled Samples, from Analytical Chemistry, vol 36, May 1964, pp. 1082-1089.
Herberg, R. J., "Statistical Aspects of Double Isotope Liquid Scintillation Counting by Internal Standard Technique", Analytical Chemistry, vol. 36, May 1964, pp. 1079-1082.

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