Surgery – Miscellaneous – Methods
Reexamination Certificate
2011-04-26
2011-04-26
Isabella, David (Department: 3774)
Surgery
Miscellaneous
Methods
C514S054000, C623S011110, C623S014120, C623S023720, C623S023750
Reexamination Certificate
active
07931030
ABSTRACT:
The invention provides viscosupplementation methods for treating osteoarthritis and joint injury with HA-based viscosupplements, particularly viscosupplements with an intra-articular residence half-life shorter than 3 weeks. Viscosupplements for use in the methods of the invention may be further characterized in that they contain less than 20 mg/ml HA, at least 5% (w/w) of which is in a gel form, such as, e.g., hylan B. In an illustrative embodiment, hylan G-F 20 (Synvisc®) is administered in a single intra-articular knee injection of 6±2 ml.
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Hamburger et al, “I
Creagan B. Timothy
Genzyme Corporation
Isabella David
Iwamaye Andrew
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