Reductive cleavage of the exocyclic ester of UK-2A or its...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

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06916932

ABSTRACT:
A process comprising reacting compound GF-I with a reducing agent to form compound GF-II wherein Y is selected from the group consisting of H, benzyl, substituted benzyl, CH2OC1-8alkyl, CH2OC3-8cycloalkyl, allyl, tetrahydropyranyl, tetra-hydrofuranyl, substituted tetrahydropyranyl, substituted tetra-hydrofuranyl, Si(C1-4alkyl)3, and Si(Ph)x(C1-4alkyl)3-xwhere x is equal to 1, 2 or 3; and wherein said process is conducted: (a) in the presence of a reducing agent; (b) in the presence of an aprotic solvent; and (c) under reaction conditions; is provided. Additionaly, novel compounds produced therefrom are provided text:

REFERENCES:
patent: 2004/0048864 (2004-03-01), Ricks et al.
patent: 01/14339 (2001-03-01), None
Greene, et al. Protective Groups in Organic Synthesis, John Wiley & Sons, Inc. 1991, pp. 98-99.
M. Ueki, et al., UK-2A, B, C, D, Novel Antifungal Antibiotics fromStreptomycessp. 517-02 Journal of Antibiotics 1996, 49, 639.

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