Reductive amination process

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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C07D40106

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055084044

ABSTRACT:
A process of reductive amination efficiently yields an HIV protease inhibitor.

REFERENCES:
Abdel-Magid, et al., "Reductive Amination of Aldehydes and Ketones by Using Sodium Triacetoxyborohydride", Tet. Letters, vol. 31, No. 329, pp. 5595-5598, 1990.
Borch, et al., "The Cyanohydridoborate Anion as a Selective Reducing Agent", J. Am. Chem Soc., vol. 93.12, pp. 2897-2904, 1971.
March, "The Addition of Alcohols to Aldehydes and Ketones", Advanced Organic Chemistry (Third Edition), pp. 798-800, 1985.

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