Reductive alkylation of substituted anilines

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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564423, 564440, 564442, 564443, C07C 8508

Patent

active

042619262

ABSTRACT:
N-alkylated aromatic amines are produced by reductively alkylating an aromatic amine with pressurized hydrogen in the presence of a ketone, a noble metal catalyst and a promoter acid having a pKa between 0.3 and 1.5.

REFERENCES:
patent: 2213204 (1940-09-01), Carleton
patent: 2947784 (1960-08-01), Martin et al.
patent: 3450764 (1969-06-01), Altwicker
patent: 3522309 (1970-07-01), Kirby
patent: 3541153 (1970-11-01), Sandridge

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