Reduction of low density lipoproteins in biological fluids

Details Reduction of low density lipoproteins in biological fluids Reduction of low density lipoproteins in biological fluids

1987-09-25

1993-08-03

Stone, Jacqueline

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

604 5, 604 6, 435 2, 435174, 435177, 435178, 435197, 435198, A61K 3754, C12N 1110, C12N 1102, A61M 138

Patent

active

052326969

ABSTRACT:
A method and apparatus for reducing the levels of low density lipoproteins (LDL) in blood is disclosed. The LDL is contacted with an enzyme which modifies it in a manner such that the LDL is rapidly removed endogenously by the patients' own metabolic processes. The enzyme may be introduced into the patient by injection, transdermal transport, nasal insufflation and ingestion. Additionally, the enzyme may be contained in a reactor for both in vivo and extracorporeal use.

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