Reduction of liposome-induced adverse physiological reactions

Details Reduction of liposome-induced adverse physiological reactions Reduction of liposome-induced adverse physiological reactions

1994-05-20

1997-03-25

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

4284022, A61K 9127

Patent

active

056142145

ABSTRACT:
Provided herein is a method of administering a liposome composition to an animal, the method involving adminstering to the animal a liposome composition containing an adverse physiological reaction-reducing effective amount of a liposome which has, in addition to a bioactive agent, a lipid bilayer containing a lipid and a surface agent-modified molecule. An adverse physiological reaction which may be experienced by the animal upon administration of a liposome composition is reduced by way of the presence of the surface agent-modified molecule in the liposome's lipid bilayer.

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