Reduction of intravenously administered nanoparticulate-formulat

Details Reduction of intravenously administered nanoparticulate-formulat Reduction of intravenously administered nanoparticulate-formulat

1996-08-14

1998-11-10

Azpuru, Carlos

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424502, 42840221, 264 43, A61K 950, B32B 516, B01J 1302

Patent

active

058340254

ABSTRACT:
Disclosed are methods of intravenous administration of nanoparticulate drug formulations to a mammal to avoid adverse hemodynamic effects: by reducing the rate and concentration of the nanoparticles in the formulations; or by pre-treating the subject with histamine; or by pretreating the subject with a desensitizing amount of the nanoparticulate drug formulations.

REFERENCES:
patent: 5565188 (1996-10-01), Wong et al.

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