Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1998-01-21
2000-05-09
Schenkman, Leondard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514334, 514345, 514634, 514635, 514673, A61K 3150, A61K 31495
Patent
active
060604719
ABSTRACT:
Mammalian hair growth is reduced by applying to the skin an inhibitor of hypusine biosynthetic pathway.
REFERENCES:
patent: 3426137 (1969-02-01), Philpitt et al.
patent: 4039669 (1977-08-01), Beylar et al.
patent: 4139638 (1979-02-01), Neri et al.
patent: 4161540 (1979-07-01), Neri et al.
patent: 4191775 (1980-03-01), Glen
patent: 4269831 (1981-05-01), Ferrari et al.
patent: 4370315 (1983-01-01), Greff et al.
patent: 4439432 (1984-03-01), Peat
patent: 4508714 (1985-04-01), Cecic et al.
patent: 4517175 (1985-05-01), Iwabuchi et al.
patent: 4720489 (1988-01-01), Shander
patent: 4885289 (1989-12-01), Breur et al.
patent: 4935231 (1990-06-01), Pigiet
patent: 5095007 (1992-03-01), Ahluwalia
patent: 5096911 (1992-03-01), Ahluwalia et al.
patent: 5132293 (1992-07-01), Shander et al.
patent: 5143925 (1992-09-01), Shander et al.
patent: 5189212 (1993-02-01), Ruenitz
patent: 5271942 (1993-12-01), Haverhagen
patent: 5300284 (1994-04-01), Wiechers et al.
patent: 5364885 (1994-11-01), Ahluwalia et al.
patent: 5411991 (1995-05-01), Shander et al.
patent: 5455234 (1995-10-01), Ahluwalia et al.
patent: 5474763 (1995-12-01), Shander et al.
patent: 5648394 (1997-07-01), Boxall et al.
patent: 5885982 (1999-03-01), Dolynchuk et al.
H.L. Cooper, "Indentification of the hypusine-containing protein HY+ as translation initiation factor elF-4D" Proc. Natl. Acad. Sci. USA, vol. 80, pp. 1854-1857, 1983.
Sakurai et al., Pharmalogical study of 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone ethanolamine salt, Chemical Abstracts, vol. 83, No. 7, Aug. 18, 1975, Abstract No. 53538.
Fleming et al--"Journal of Cardiovascular Pharmacology" 10 Suppl 10 5149-53 (Abstract), 1987.
Yoshimasa et al--"J. SccJ," 22(3), 165-70 (Japan) (Abstract), 1988.
Bogaert et al--"Journal of International Medical Research" 14(4) 210-6 (U.K.) (Abstract), 1986.
Ransom et al--"Synapse", 5 (4), 294-8 (Abstract), 1990.
Csonga et al., "Evaluation of the metal ion requirement of the human deoxyhypusine hydroxylase from HeLa cells using a novel enzyme assay", FEBS Letters, 380 (1996) 209-214.
Joe et al., "Structural Features of the elF-5A Precursor Required for Posttranslational Synthesis of Deoxyhypusine", The Journal of Biological Chemistry, vol. 269, No. 41, Oct. 14, 1994, pp. 25916-21.
Jakus et al., "Features of the Spermidine-binding Site in Deoxyhypusine Synthase as Derived from Inhibition Studies", The Journal of Biological Chemistry, vol. 268, No. 18, Jun. 18, 1993, pp. 13154-59.
Andrew G. Messenger, "The Control of Hair Growth: An Overview", The Society for Investigative Dermatology, Inc., 1993.
Park et al., "Hypusine: its post-translational formation in eukaryotic initiation factor 5A and its potential role in cellular regulation", Biofactors, 4:95-104 (1993).
Paz et al., "Hydralazine Inhibition of the Post-Translational Hydroxylation of Deoxyhypusine, A Polyamine-Derived Amino Acid", Biochemical Pharmacology, vol. 33, No. 5, pp. 779-95, 1984.
Adachi et al., "Human Hair Follicles: Metabolism and Control Mechanisms", Journal of the Society of Cosmetic Chemists, 21, 901-924, Dec. 9, 1970.
Ahluwalia Gurpreet S.
Shander Douglas
Styczynski Peter
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