Reduction of false positives in oral-fluid based immunoassays

Details Reduction of false positives in oral-fluid based immunoassays Reduction of false positives in oral-fluid based immunoassays

1996-09-04

1999-02-16

Smith, Lynette F.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 6, 435 71, 435 72, 128760, 128771, C12Q 170, C12Q 168, G01N 3353, A61B 500

Patent

active

058719059

ABSTRACT:
This invention relates to the use and composition of materials which, when added to oral fluid samples, make such samples suitable for use with microparticle-based immunoassays. In one embodiment, this invention provides a method of reducing false positives in assays for the detection of an analyte in an oral fluid sample. The method involves providing an oral fluid sample combined with a bile acid or salt where the bile acid or salt is present in a concentration sufficient to reduce the rate of occurrence of false positives in said oral fluid based immunoassays.

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