Reduction of diffusional defocusing in hydrodynamically focused

Fluid handling – Processes – Involving pressure control

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137567, 137806, 137828, F15C 120

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active

057996822

ABSTRACT:
An analyte fluid stream with first molecules having relatively low molecular weight and a corresponding high coefficient of diffusion has reduced diffusional defocusing out of an analyte fluid stream. The analyte fluid stream of first molecules is associated with second molecules of relatively high molecular weight having a relatively low coefficient of diffusion and a binding constant effective to associate with the first molecules. A focused analyte fluid stream is maintained since the combined molecular weight of the associated first and second molecules is effective to minimize diffusion of the first molecules out of the analyte fluid stream.

REFERENCES:
patent: 3123285 (1964-03-01), Lee
patent: 3334641 (1967-08-01), Bjornsen
patent: 3548851 (1970-12-01), Sampson
patent: 5637208 (1997-06-01), Dourdeville
patent: 5641006 (1997-06-01), Autrey et al.

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