Reduction of carbonyl compounds using the carbonyl reductase...

Details Reduction of carbonyl compounds using the carbonyl reductase... Reduction of carbonyl compounds using the carbonyl reductase...

2006-08-22

2006-08-22

Saeed, Kamal A. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S485000

Reexamination Certificate

active

07094908

ABSTRACT:
A compound represented by a general formula (Ia) or (Ib) and a stereo-selective preparation method thereof using a carbonyl reductase which is separated fromKluyveromyces marxianus. The compound can be prepared by reduction of substituted β-keto ester and can be used as an intermediate in preparing β-lactam group antibiotics.

REFERENCES:
patent: 4927507 (1990-05-01), Schneider et al.
Lubouch et al., Aminocarboxyclic Acids. IX. Conformational Studies of RR,SS,and RS,SR-Beta- Hydroxyaspartic Acid Derivatives. Roczniki chemli (1974), 48(12), 2181-9.
Walter Durckheimer, et al., “Recent Developments in the Field of B-Lactam Antibiotics”, Angew. Chem. Int. End. Engl. 24 (1985) 180-202.
Paul J. Reider, et al., “Total Synthesis of Thienamycin: A New Approach From Aspartic Acid”, Tetrahedron Letters, vol. 23, No. 22, pp. 2293-2296, 1982.
R. Noyori, et al., “Stereoselective Hydrogenation via dynamic Kinetic Resolution”, J. Am. Chem. Soc. 1989, 111, pp. 9134-9135.
Isao Sada, et al., “Process for preparing 4-acetoxy-3-hydroxyethylazatidin-2-one derivatives as antibiotic intermediates”, Chem. Abstr., 1989, 110(17), 154035a.
Masayoshi Murata, et al., “Process for preparing optically active 3-substituted azetidinones”, Chem. Abstr., 1991, 115(11), 112844c.
S. Servi, “Baker's Yeast as a Reagent in Organic Synthesis”, Synthesis, 1990, pp. 1-25.
R. Cauk, et al., “Baker's Yeast Mediated Transformations in Organic Chemistry”, Chem. Rev. 1991, vol. 91, pp. 49-97.

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