Reductase gene and use of the same

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

Reexamination Certificate

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C435S148000, C435S155000, C435S156000, C435S161000, C435S170000, C435S189000, C435S320100, C435S325000, C435S440000, C435S252300, C536S023200

Reexamination Certificate

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10782998

ABSTRACT:
A gene containing a DNA having the nucleotide sequence encoding any one of the amino acid sequences of the following (a) to (e):(a) an amino acid sequence set out in SEQ ID NO: 1;(b) an amino acid sequence having the sequence homology of 80% or more with (a);(c) an amino acid sequence having the sequence homology of 90% or more with (a);(d) an amino acid sequence encoded by a DNA having the nucleotide sequence set out in SEQ ID NO: 2;(e) an amino acid sequence encoded by a DNA having the nucleotide sequence having the sequence homology of 80% or more with (d).

REFERENCES:
patent: 5385833 (1995-01-01), Bradshaw et al.
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Umeyama, T., et al., “Orf1, orf2, orf3, orf4, orf5 genes”, The University of Tokyo, Department of Biotechnology, Division of Agriculture and Life Sciences (May 2000).
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Nakamura, et al., “Different Stereochemistry for the Reduction of Trifluoromethyl Ketones and MEthyl Ketones Catalyzed by Alcohol Dehydrogenase fromGeotrichum”, Tetrahedron Letters, vol. 37, No. 32, pp. 5727-5730 (1996).

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