Reducing non-specific binding in immunoassays performed on...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S007940, C435S962000, C436S518000, C436S524000

Reexamination Certificate

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06984497

ABSTRACT:
Water-soluble polymer is added to the liquid phase in a heterogeneous a immunoassay of serum, the polymer having monomers in common with monomers of the solid phase surface. This reduces non-specific binding of IgG's from the serum to the solid phase surface and thereby reduces the occurrence of false positive readings in the immunoassay.

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patent: WO 01/79844 (2001-10-01), None
Wild., The Immunoassay Handbook, Surface-coated solid-phases, pp. 59-62, M stockton press, 1994.
Nunc Products Online Catalog, 96 MicroWell Plates catalog No. 262162, Jul. 8, 2004, www.nuncbrand.com.
Bangs Laboratories, Inc. “Working with Microspheres,”Technote#201 Aug. 29, 1999, pp. 1-16.

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