Reducing myelin-mediated inhibition of axon regeneration

Details Reducing myelin-mediated inhibition of axon regeneration Reducing myelin-mediated inhibition of axon regeneration

2007-12-18

2007-12-18

Chernyshev, Olga N. (Department: 1649)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

C424S184100, C424S185100, C435S007100, C435S007210

Reexamination Certificate

active

10127058

ABSTRACT:
Oligodendrocyte-myelin glycoprotein (OMgp)-specific binding agents are used to reduce OMgp-mediated axon growth inhibition. Mixtures of axons and OMgp and mixtures of Nogo receptor (NgR) and OMgp are used in pharmaceutical screens to characterize agents as inhibiting binding of NgR to OMgp and promoting axon regeneration.

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