Reducing axon degeneration with proteasome inhibitors

Details Reducing axon degeneration with proteasome inhibitors Reducing axon degeneration with proteasome inhibitors

2006-03-14

2006-03-14

Campell, Bruce R. (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S002600, C514S125000, C530S300000

Reexamination Certificate

active

07012063

ABSTRACT:
Reduced degeneration of an axon predetermined to be subject to degenerative neuropathy in a term patient is effected by contacting the axon in situ with an effective amount of a ubiquitin-proteasome system (UPS) inhibitor sufficient to reduce degeneration of the axon; and detecting a resultant reduction in the degeneration of the axon in situ.

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