Reduced naphthalenes, their preparation and use

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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260465F, 260465R, 549 78, 549445, 549497, 560256, 562462, 564217, 564428, 424275, 424278, 424282, 424305, 424317, 424320, 424331, 568327, A61K 31135

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043820948

ABSTRACT:
A compound of the formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein: Ar is phenyl, optionally substituted by one or more C.sub.1-4 alkyl, C.sub.1-4 alkoxy, halogen, cyano, nitro, hydroxy, CONH.sub.2, CO.sub.2 W wherein W is C.sub.1-6 alkyl or C.sub.1-4 alkylphenyl which phenyl may be substituted by one or more C.sub.1-4 alkyl, C.sub.1-4 alkoxy or halogen, NR.sub.1 R.sub.2 wherein R.sub.1 and R.sub.2 are selected from hydrogen or C.sub.1-6 alkyl, NHCO C.sub.1-6 alkyl or C.sub.1-6 alkylcarbonyloxy; phenyl disubstituted on adjacent carbon atoms by methylenedioxy; furyl or thienyl;

REFERENCES:
patent: 3833726 (1974-09-01), Schwender et al.
patent: 3843665 (1974-10-01), Coombs et al.
patent: 4177271 (1979-12-01), Vallet
patent: 4201869 (1980-05-01), Cohen et al.

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