Reduced and controlled surface binding of biologically active mo

Details Reduced and controlled surface binding of biologically active mo Reduced and controlled surface binding of biologically active mo

1993-03-11

1995-08-15

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

424422, 424423, 424461, 424493, 424494, 600 30, 6048911, 604 8, 604 43, 604327, 604403, 606 1, 606 14, 607 2, A61K 900

Patent

active

054417392

ABSTRACT:
Articles of manufacture which are adapted for use in contact with one or more biologically active agents are coated with a glassy carbohydrate film. The glassy film provides a reduced surface energy coating which exhibits a reduced degree of binding with biologically active agents. Methods for applying the glassy carbohydrate film are disclosed wherein the glassy film is adsorbed directly onto the article surface. The coated articles are for use both in vitro and in vivo where contact with biologically active agents is expected.

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