Reduced A ring-.DELTA..sup.9(11) -corticoids

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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26023955R, 26023955D, 424243, C07J 700

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active

044275919

ABSTRACT:
17.alpha.-Acyloxy-5.beta.-pregnanes (I) and 17.alpha.-acyloxy-5.alpha.-pregnanes (IV) have an excellent activity split providing high topical anti-inflammatory activity with very low systemic side effects.

REFERENCES:
patent: 3055922 (1970-03-01), Krakower et al.
patent: 3992422 (1976-11-01), Green et al.
patent: 4336200 (1982-06-01), Ayer et al.

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