Redirection of cellular immunity by receptor chimeras

Details Redirection of cellular immunity by receptor chimeras Redirection of cellular immunity by receptor chimeras

1995-04-05

1998-12-01

Carlson, Karen Cochrane

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using tissue cell culture to make a protein or polypeptide

435 691, 4353201, 435325, 530350, 536 231, C02P 2102, C12N 522, C07K 14705, C07H 1700

Patent

active

058437282

ABSTRACT:
Disclosed is a method of directing a cellular response in a mammal by expressing in a cell of the mammal a chimeric receptor which causes the cells to specifically recognize and destroy an infective agent, a cell infected with an infective agent, a tumor or cancerous cell, or an autoimmune-generated cell. Also disclosed are cells which express the chimeric receptors and DNA encoding the chimeric receptors.

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