Red-emitting [8,9]benzophenoxazine nucleic acid dyes and methods

Details Red-emitting [8,9]benzophenoxazine nucleic acid dyes and methods Red-emitting [8,9]benzophenoxazine nucleic acid dyes and methods

1999-09-03

2000-10-31

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544 98, C07D26534, C07D26528

Patent

active

061405000

ABSTRACT:
A new class of red-emitting, fluorescent [8,9]benzophenoxazine dyes are provided that are useful for staining nucleic acids in a variety of contexts, including in solutions, in electrophoretic gels or other matrices, in blotting experiments and in assays employing intact, live cells. The new dyes are brighter and permeate cells faster than currently available red-emitting live-cell nucleic acid stains.

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