Red blood cell filtering system

Details Red blood cell filtering system Red blood cell filtering system

1987-05-26

1989-03-07

Jones, W. Gary

Liquid purification or separation

With means to add treating material

With distinct reactor tank, trough or compartment

2102571, 210446, 210483, 210508, 422 44, 422101, 604406, 604410, B01D 2126, B01D 2908, B01D 3600

Patent

active

048103780

ABSTRACT:
Closed filtering system for relatively fast and efficient removal of white blood cells from a red blood cell mixture. System comprises at least two blood bags in closed communication with each other via an intermediate filter assembly comprising a housing containing continuous filtering fiber. A preferred housing is tapered and the fiber preferably has a generally Y-shaped cross sectional area and it is adapted to permit substantial removal of white blood cells from a red blood cell mixture with minimal red blood cell hemolysis when the mixture is diluted with preservative solution and passed from one bag to the other at a relatively high flow rate. Filtration is completed within 24 hours, preferably within 6 hours, of whole blood donation.

REFERENCES:
patent: 3448041 (1969-06-01), Swank
patent: 4155854 (1979-05-01), Marx
patent: 4170056 (1979-10-01), Meyst et al.
patent: 4330410 (1982-05-01), Takenuka
patent: 4596657 (1986-06-01), Wisdom
Beutler, E. et al., "The Mechanism of Removal of Leukocytes by Cellulose Columns", Blood Cells, 12:57-64 (1986).

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