Organic compounds -- part of the class 532-570 series – Organic compounds – Heavy metal containing
Reexamination Certificate
2005-09-06
2005-09-06
Nazario-Gonzalez, Porfirio (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heavy metal containing
C556S136000, C558S357000, C558S462000, C548S103000
Reexamination Certificate
active
06939982
ABSTRACT:
The present invention relates to chiral metal catalysts for stereoselective olefin metathesis reactions, which are recyclable and reusable in such metathesis reactions. The chiral metal-based metathesis catalysts of the invention comprise multidentate optically active or racemic chiral ligands that enable their use in asymmetric synthetic processes, such as for example, in ring-opening and ring-closing metathesis reactions (ROM and RCM, respectively) of alkenes. The catalysts of the invention are organometallic complexes of multivalent metals comprising one or more chiral bidentate ligands that exhibit superior reactivity and stereoselectivity properties. The present invention also provides methods of making such catalysts and methods for utilizing them in catalyzing stereoselective olefin metathesis reactions to provide asymmetric products in relatively high enantiomeric or stereoisomeric excess.
REFERENCES:
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Garber Steven B.
Hoveyda Amir H.
Kingsbury Jason S.
Van Veldhuizen Joshua
Campbell Evans Paula
Dykeman David J.
Nazario-Gonzalez Porfirio
Palmer & Dodge LLP
The Trustees of Boston College
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