Rectal dosage form

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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Details

424DIG15, 514198, 514199, 514200, 514965, 514966, 514970, A61K 902, A61K 4700

Patent

active

047600594

ABSTRACT:
The rectal absorption of the beta-lactam antibiotic ceftriaxone in a solid dosage form is enhanced with chenodeoxycholic acid or its sodium salt, in the presence of a carrier consisting of a mixture of two or more glycerides of C.sub.12 to C.sub.18 fatty acids.

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patent: 4579730 (1986-04-01), Kidron et al.
Fuller C.A. 103, #200886A (1985) of EP 152896 28 Aug. 1985, (Swiss 22 Feb. 1984), 22 pp.
Sekine C.A. 103, #189155p (1985) of J. Pharmacobio-Dyn 8(8): 653-660 (1985).
Sankyo C.A. 102, #154814e (1985) of JP 59227822, 21 Dec. 1984, 7 pp.
Murakami et al. GA 101, #48186w (1984) of Chem. Pharm. Bull. 32 (5): 1948-1955 (1984).
Yata C.A. 100, #26030t (1984) of EP 91502, 19 Oct. 1983, 38 pp.
Higuchi et al. C.A. 100, #12654n (1984) of U.S. 4406896, 27 Sep. 1983, 12 pp.
Toyojozo C.A. 97, #150726h (1982) of JP 82 99519, 21 Jun. 1982, 5 pp.
Kawamura et al. C.A. 87, #189465r (1977) of Japan Kokai 77 83923, 13 Jul. 1977, 4 pp.

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