Recovery of taxanes from plant material

Details Recovery of taxanes from plant material Recovery of taxanes from plant material

1997-11-18

1999-11-09

Trinh, Ba K.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549511, C07D30514

Patent

active

059817771

ABSTRACT:
The present invention provides new methods isolating taxanes and other metabolites from taxane-producing plant materials.

REFERENCES:
patent: 5547866 (1996-08-01), Durzan et al.
patent: 5670663 (1997-09-01), Durzan et al.
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Guo et al. (1994) Biol. Chem. Hoppe. Seyler, 374(4): 281-7.
Zenkteler, M., et al. "Cytological studies n the regenerating mature female gametophyte of Taxus baccata L. and mature endosperm of Tilia platyphyllos Scop. in vitro culture," Acta Sacietatis Botanicorum Poloniae, 1:161-173 (1970).
Gibson, D. et al. "Initiation and growth of cell lines of Taxus brevifolia (Pacific yew)," Plant Cell Reports, 12:479-482, 1993.
Fett-Neto, A. et al., "Improved Growth and Taxol Yield in Developing Calli of Taxus cuspidata by Medium Composition Modification," Bio/Technology, 11:731-734, 1993.
Fett-Neto, A., "Cell Culture of Taxus as a Source of the Antineoplastic Drug Taxol and Related Taxanes," Biotechnology, 10:1572-1575, 1992.
Byrde, R., (1979) "Role of Polysaccharide-Degrading Enzymes in Microbial Pathogenicity," Microbial Polysaccharides and Polysaccharases (Chapter 18):422-424 (1991-92) "Technical Information," Sigma Plant Cell Culture 49-59.
Rohr, R., "Activation et proliferation des cellules du megagametophyte de Taxus cultive in vitro," Can. J. Bot., 60:1583-1589, 1982.
Durzan and Ventimiglia, In Vitro Cell Dev. Biol. 30:219-227 (1994).

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