Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Recovery or purification
Patent
1979-03-09
1980-08-12
Castel, Benoit
Chemistry: molecular biology and microbiology
Virus or bacteriophage, except for viral vector or...
Recovery or purification
260112B, 424 89, 210 78, A61K 3912, C12K 700
Patent
active
042174180
ABSTRACT:
It has now been found that small size particles may be extracted from a proteinaceous liquid at a low flow rate in flow-centrifuge operation by precooling the liquid before it enters the centrifuge and by employing a multi-step gradient.
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patent: 4113712 (1978-09-01), Funakoshi
Nat. Cancer Institute Monogram 21: pp. 253-283 (1966).
Takahashi et al., "Large Scale Isolation of Dane Particles from Plasma Containing Hepatitis B Antigen and Demonstration of a Circular Double Stranded DNA Molecule Extruding Directly from their Cores"; Journal of Immunology, vol. 117, No. 4, Oct. 1976, pp. 1392-1397.
Hurni William M.
McAleer William J.
Castel Benoit
Levitt Julian S.
Merck & Co. , Inc.
Perrella Donald J.
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