Recovery of fetal cells from maternal blood using chaotic...

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se

Reexamination Certificate

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C435S261000, C435S394000, C435S286700, C210S787000

Reexamination Certificate

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06890755

ABSTRACT:
To extract fetal cells from a sample of maternal blood or a fluid derived from maternal blood, sample liquid is moved over a collector surface bearing a ligand for the fetal cells. Chaotic advection in the liquid enhances the efficiency of cell collection.

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patent: 5684712 (1997-11-01), Goffe et al.
Chaiken et al., “Experimental Study of Lagrangian Turbulence in a Stokes Flow,” Proc. R. Soc. Lond. A408:165-174 (1986).
Gomez, 1999 “Attachment of Cells to Surfaces under Controlled Fluid Flows,” Graduate Thesis, Columbia University.

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