Recovering purified antibodies from egg yolk

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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A23J 109, A61K 3900, C07G 700, G01N 3354

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043572723

ABSTRACT:
Immunological preparations are prepared by immunizing hens with an antigen, preferably to a stage of hyperimmunization. The eggs of the immunized hens are collected, the yolk is separated from the eggs, followed by separation of the lipid content of the yolk. The antibodies in the egg yolk are then rendered indispersable with the aid of a water-soluble linear filamentary non-charged polymer precipitant such as PEG and the indispersable antibodies are recovered. This precipitation of antibodies is preferably preceded by a precipitation of caseinaceous proteins at lower polymer concentrations.
The immunological preparations are useful for diagnostic purposes and in appropriate cases also for the treatment of pathological conditions.

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