Reconstructed epidermis/skin equivalent comprising a...

Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Skin cosmetic coating

Reexamination Certificate

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C424S401000, C424S450000, C424S811000, C435S371000, C514S474000, C514S943000

Reexamination Certificate

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10766016

ABSTRACT:
A reconstructed epidermis/skin equivalent supplemented with at least one ceramide 7 and/or 5.5 compound, suited for reinforcing the barrier function of normal human epidermis and for improving the barrier function of dry skin and of reconstructed skin or skin equivalents, is prepared by introducing the at least one ceramide 7 and/or 5.5 compound into the culture medium of such reconstructed epidermis/skin equivalent and/or topically applying onto the face surface of such reconstructed epidermis/skin equivalent a composition which comprises lipid lamellar vesicles incorporating at least one ceramide 7 and/or 5.5 compound.

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Dreher et al., “Comparison of Cutaneous Bioavailability of Cosmetic Preparations Containing Caffeien or α-Tocopherol Applied on Human Skin Models or Human Skinex vivoat Finite Doses”, Skin Pharmacology and Skin Applied Physiology, vol. 15, No. Suppl. 1, 2002 pp. 40-58.
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French Search Report Corresponding to FR 03/01059 Issued on Dec. 17, 2003, 2 Pages.

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