Reconstituted HDL particles and uses thereof

Details Reconstituted HDL particles and uses thereof Reconstituted HDL particles and uses thereof

1988-10-27

1992-07-07

Russel, Jeffrey E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

424450, 436829, 514 21, A61K 3702

Patent

active

051283182

ABSTRACT:
A reconstituted high density lipoprotein containing particle is disclosed. The particle is useful in removing excess lipid soluble material from a subject to which it is administered, as well as in delivery of lipid soluble pharmaceuticals to subjects or patients.

REFERENCES:
patent: 4499184 (1985-02-01), Goodhue
patent: 4789545 (1988-12-01), Woods et al.
patent: 4943527 (1990-07-01), Protter et al.
Zinsser Microbiology, 19th ed. Joklik et al, eds. Appleton & Lange, 1988, p. 335.
Raetz, "Biochemistry of Endotoxins," Annu. Rev. Biochem. 1990, vol. 59, pp. 129-130.
Malmendier et al., "In vivo metabolism of human apoprotein A-I-phospholipid complexes, Comparison with human high density lipoprotein-apoprotein A-I metabolism," Clinica Chimica Acta, vol. 131, No. 3 (1983), pp. 200-211.
Segrest et al, Methods in Enzymology, Academic Press 1986, vol. 128, pp. 3-41, 223-246, 554-582.
Williams et al, "Uptake of endogenous cholesterol by a synthetic lipoprotein," Biochemica et Biophysica Acta 875 (1986), pp. 183-194.
Matz et al, "Micellar Complexes of Human Apolipoprotein A-I with Phosphatidylcholine and Cholesterol Prepared from Cholate-Lipid Dispersions," J. Biological Chemistry, vol. 257, No. 8, Apr. 25, 1982, pp. 4535-4540.
Matz et al, "Reaction of Human Lecithin Cholesterol Acyltransferase with Synthetic Micellar Complexes of Apolipoprotein A-I, Phosphatidycholine, and Cholesterol, " J. Biological Chemistry, vol. 257, No. 8, Apr. 25, 1982, pp. 4541-4546.

Affiliated with

Also associated with

Rating

Reconstituted HDL particles and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Reconstituted HDL particles and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Reconstituted HDL particles and uses thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1829832