Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Reexamination Certificate
2005-09-22
2009-11-10
Yang, N (Department: 1641)
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
C435S006120, C435S285200, C422S052000, C422S082080, C436S518000, C436S524000, C436S534000, C436S172000
Reexamination Certificate
active
07615369
ABSTRACT:
A protein patterning electrode device consisting of capacitor microelectrode arrays coated with a protein non-adherent layer is provided. Operation of the electrode is based on a phenomenon called “electrowetting,” where surface wettability can dynamically be controlled by varying the voltage across the device electrodes. When an electric field is applied across the electrode layers, the surface accumulates charge and becomes hydrophilic, binding the proteins to the surface via ionic bonding. Electrically controlling the amount of the surface charge permits controlled protein surface affinity. The device provides a means for reconfigurable protein patterning.
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Fan Chao Yung
Frost Amaya
Kurabayashi Katsuo
Lin Chih-Tin
Meyhöfer Edgar
Brooks & Kushman P.C.
The Regents of the University of Michigan
Yang N
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