Recombination systems and methods for eliminating nucleic...

Details Recombination systems and methods for eliminating nucleic... Recombination systems and methods for eliminating nucleic...

2004-01-05

2010-06-15

Grunberg, Anne Marie (Department: 1638)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Fungi

C435S463000, C435S257200, C435S477000, C435S478000

Reexamination Certificate

active

07736886

ABSTRACT:
The invention relates to recombination systems and methods for eliminating nucleic acid sequences from the chromosomal DNA of eukaryotic organisms, and to transgenic organisms—preferably plants—which comprise these systems or were generated using these methods.

REFERENCES:
patent: 5527695 (1996-06-01), Hodges et al.
patent: 5792632 (1998-08-01), Dujon et al.
patent: 6395959 (2002-05-01), Dujon et al.
patent: WO 96/14408 (1996-05-01), None
Lyznik et al. 1996, Nucleic Acids Research 24:3784-3789.
Puchta, H., et al., “Two Different but related mechanisms are used in plants for the repair of genomic double-strand breaks by homologous recombination”, Proc. Natl. Acad. Sci. USA, vol. 93, 1996, pp. 5055-5060.
Aggarwal, A., et al., “Novel site-specific DNA endonucleases”, Current Opinion in Structural Biology, vol. 8, 1998, pp. 19-25.
Russell, S., et al. “Directed Excision of a Transgene from the Plant Genome”, Mol. Genet. Genet. vol. 234, 1992, pp. 49-59.
Kilby, N., et al., “FLP Recombinase in Transgenic Plants: Constitutive Activity in Stably Transformed Tobacco and Generation of Marked Cell Clones in Arabidopsis”, The Plant Journal, vol. 8, No. 5, 1995, pp. 637-652.
Onouchi, H., et al., “Visualization of Site-Specific Recombination Catalyzed by a Recombinase fromZygosaccharomyces rouxiiinArabidopsis thaliana”, Mol. Gen. Genet. vol. 247, 1995, pp. 653-660.
Haber, J., “In Vivo Biochemistry: Physical Monitoring of Recombination Induced by Site-Specific Endonucleases”, BioEssays, vol. 17, No. 7, 1995, pp. 609-620.
Puchta, H., “Use of I-Sce I to Induce DNA Double-Strand Breaks in Nicotiana”, Chapter 36, in Methods in Molecular Biology, vol. 113, DNA Repair Protocols: Euroacryotic Systems, Henderson, D.S., ed., Humana Press Inc., NJ, USA, 1999, pp. 447-451.
Segal, D., et al., “Endonuclease-induced, Targeted Homologous Extrachromosomal Recombination inXenopusOocytes”, Proc. Natl. Acad. Sci. USA, vol. 92, 1995, pp. 806-810.
Kuzminov, A., “Recombinational Repair of DNA Damage inEscherichla coliand Bacteriophageλ”, Microbiology and Molecular Biology Reviews, vol. 63, No. 4, 1999, pp. 751-813.
Heifetz, P., et al., “Protein Expression in Plastids”, Current Opinion in Plant Biology, vol. 4, 2001, pp. 157-161.
Mengiste, T., et al., “Prospects for the Precise Engineering of Plant Genomes by Homologous Recombination”, Biol. Chem., vol. 380, 1999, pp. 749-758.
Hohn, B., et al., “Gene Therapy in Plants”, Proc. Natl. Acad. Sci. USA, vol. 96, 1999, pp. 8321-8323.
Puchta, H., et al., “From CentiMorgans to Base Pairs: Homologous Recombination in Plants”, Trends in Plant Science, vol. 1, No. 10, 1996, pp. 340-348.
Siebert, R., et al., “Efficient Repair of Genomic Double-Strand Breaks by Homologous Recombination between Directly Repeated Sequences in the Plant Genome”, The Plant Cell, vol. 14, 2002, pp. 1121-1131.
Dale, E., et al., “Gene Transfer with Subsequent Removal of the Selection Gene from the Host Genome”, Proc. Natl. Acad. Sci. USA, vol. 88, 1991, pp. 10558-10562.
Osborne, B., et al., “A System for Insertional Mutagenesis and Chromosomal Rearrangement Using the Ds Transposon and Cre-lox”, The Plant Journal, vol. 7, No. 4, 1995, 687-701.
Lyznik, L.A., et al., “FLP-Mediated Recombination ofFRTSites in the Maize Genome”, Nucleic Acids Research, vol. 24, No. 19, 1996, pp. 3784-3789.
Sugita, K. , et al., “A transformation Vector for the Production of Marker-Free Transgenic Plants Containing a Single Copy Transgene at High Frequency”, The Plant Journal, vol. 22, No. 5, 2000, pp. 461-469.
Jasin, M., “Genetic Manipulation of Genomes with Rare-Cutting Endonucleases”, TIG, vol. 12, No. 6, 1996, pp. 224-228.
Bibikova, M., et al., “Stimulation of Homologous Recombination through Targeted Cleavage by Chimeric Nucleases”, Molecular and Cellular Biology, vol. 21, No. 1, 2001, pp. 289-297.
Posfai, G., et al., “Markerless Gene Replacement inEscherichia coliStimulated by a Double-Strand Break in the Chromosome”, Nucleic Acids Research, vol. 27, No. 22, 1999, pp. 4409-4415.
Dürrenberger, F. et al., “Double Strand Break-Induced Recombination inChlamydomonas reinhardtiiChloroplasts”, Nucleic Acids Research, vol. 24, No. 17, 1996, pp. 3323-3331.
Kanaar, R., et al., “Recombination and Joining: Different Means to the Same Ends”, Genes and Function, vol. 1, No. 3, 1997, pp. 165-174.
Vergunst, A.C., et al., “Recombination in the Plant Genome and its Application in Biotechnology”, Critical Reviews in Plant Sciences, vol. 18, No. 1, 1999, pp. 1-31.
Roth, D., et al., “Illegitimate Recombination in Mammalian Cells”, Chapter 21 in Genetic Kucherlapatl, R., et al., eds., Washington, 1988, pp. 621-635.
Puchta, H., “Removing Selectable Marker Genes: Taking the Shortcut”, Trends in Plant Science, vol. 5, No. 7, 2000, p. 273-274.

Affiliated with

Also associated with

Rating

Recombination systems and methods for eliminating nucleic... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Recombination systems and methods for eliminating nucleic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombination systems and methods for eliminating nucleic... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4237277