Recombination activating gene deficient mouse

Multicellular living organisms and unmodified parts thereof and – Nonhuman animal

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800DIG1, 800DIG3, 4351723, 4353201, 424 92, 4242041, 4242341, 935111, C12N 1500, A61K 4900, A61K 3900

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active

055832784

ABSTRACT:
This invention relates to a recombinant mouse with both alleles of recombination activating gene 2 being functionally deficient. This invention discloses the method to make such mouse and the uses of such mouse.

REFERENCES:
Koller et al., Science 248: 1227-1230 (1990).
Zimmer et al., Nature 338: 150-153 (1989).
Robertson, Biology of Reproduction 44: 238-245 (1991).
Andriole, Amer. J. Medicine 82(4A): 67-70 (1987).
Biederman, K. A., et al., Proc. Natl. Acad. Sci., U.S.A., vol. 88, pp. 1394-1397 (1991).
Blackwell, T. K., et al., J. Biol. Chem., vol. 264, pp. 10327-10330 (1989).
Bosma, M. J., et al., Annu. Rev. Immunol. vol. 9, pp. 323-350 (1990).
Carroll, A. M., et al., Genes Dev., vol. 5, pp. 1357-1366 (1991).
Ferrier, P., et al., J. Exp. Med., vol. 171, pp. 1900-1918 (1990).
Fulop, G. M., et al., Nature, vol. 347, pp. 479-482 (1990).
Hardy, R. R., et al., Cur. Topics in Microbiol. & Immunol., vol. 152, pp. 19-251 (1989).
Lewis, S., et al., Cell, vol. 59, pp. 585-588 (1989).
Lieber, M. R., et al., Genes Dev., vol. 1, pp. 751-761 (1987).
London, N. J. M., et al., Transplant Proc., vol. 23, pp. 749 (1991).
McCune, J. M., Curr. Opin. Immunol., vol. 3, pp. 224-228 (1991).
Oettinger, M. A., et al., Science, vol. 248, pp. 1517-1523 (1990).
Phillips, R. A., et al., Curr. Top. Microbiol. Immunol. vol. 152, pp. 259-263 (1989).
Turka, L. A., et al., Science, vol. 253, pp. 778-781 (1991).

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