Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2007-09-25
2007-09-25
Ketter, James (Department: 1636)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S320100
Reexamination Certificate
active
11157741
ABSTRACT:
The present invention relates to a recombinant vector comprising MJ1 gene coding an integrase derived fromEnterococcustemperate bacteriophage φ FC1 and an integration method using the vector. More particularly, the present invention relates to a recombinant vector comprising MJ1 gene which can make a site-specific integration in the human cell independently without other factors but not cause an excision and an integration method using the vector. Therefore, the present invention can be very useful in gene therapy in mammalian animal.
REFERENCES:
Yang et al., Journal of Bacteriology, vol. 184, No. 7, 2002, pp. 1859-1864.
Chang Hyo Ihl
Choi Hyo Sook
Clark & Elbing LLP
Ketter James
Korea University Industry and Academy Cooperation Foundation
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