Recombinant vaccinia virus expressing human retrovirus gene

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant virus encoding one or more heterologous proteins...

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424 932, 435 693, 4353201, A61K 3921, A61K 39295, C12N 1586, C12P 2102

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active

057702101

ABSTRACT:
A recombinant vaccinia virus capable of expressing HTLV-III envelope protein (env) has been constructed. The expressed env protein is recognized by sera obtained from AIDS patients. The synthesized env protein also produces antibodies when administered to a suitable host, such antibodies having specific binding affinity with the env protein.

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