Recombinant vaccinia virus expressing E-protein of Japanese ence

Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or...

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424 89, C12N 701

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active

050213474

ABSTRACT:
There is provided a recombinant vaccinia virus having inserted cDNA coding for E-protein of Japanese encephalitis virus into a genome region non-essential to growth of a vaccinia virus, in the form of capable expression. The recombinant vaccinia virus is useful as a live vaccine.

REFERENCES:
patent: 4603112 (1986-07-01), Paolletti
patent: 4659569 (1987-04-01), Mitsuhashi
patent: 4810492 (1989-03-01), Fujita
Mason, P. W. et al., Jun. 1987, Virology, 158(2), 361-372.
Sumiyoshi, H. et al., Dec. 1987, Virology, 161(2), 497-510.
Sumiyoshi, H. et al., 1986, Gene, 48:195-201.
McAda, P. C. et al., Jun. 1987, Virology, 158(2), 348-360.
Chemical Abstracts, 107:205157f, (1987).
Sumiyoshi et al., Gene, vol. 48, pp. 195-201, (1986).

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