Recombinant vaccinia virus encoding cytochromes P-450

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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435189, 4352402, 536 232, 935 32, 935 60, 935 70, C12N 902, C12N 1553, C12N 1585, C12N 1586

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active

055061389

ABSTRACT:
The present invention is related to the construction and application of vaccinia virus containing DNA sequences for encoding and efficient expression of enzymatically active cytochrome P-450 polypeptides in mammalian cells. Preparation and use of pure P1-450 and P3-450 cytochromes have been described.

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