Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1995-05-15
1997-11-25
Guzo, David
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
530350, A61K 39255, C07K 14055
Patent
active
056909390
ABSTRACT:
The invention is related to a nucleic acid sequence encoding a MD06 Marek's Disease Virus protein. Such a protein can be used for the immunization of poultry against MDV infection or disease. The nucleic acid sequence encoding the MD06 MDV protein can be applied for the preparation of the protein by means of genetic engineering techniques or can be applied for the preparation of vector vaccines.
REFERENCES:
patent: 5283191 (1994-02-01), Morgan et al.
T. Igarashi et al., "Restriction Enzyme Map of Herpesvirus of Turkey DNA and its Collinear Relationship with Marek's Disease Virus DNA," Virology, vol. 157 pp. 351-358, 1987, USA.
K. Fukuchi et al., "Structure of Marek's Disease Virus DNA: Detailed Restriction Enzyme Map," Journal of Virology, vol. 51, pp. 102-109, 1984, USA.
N. Yanagida et al., "Recombinant Fowlpox Viruses Expressing the Glycoprotein B Homolog and the pp38 Gene of Marek's Disease Virus," Journal of Virology, 66:3:1402-1408, Mar. 1992.
X. Chen et al., "Identification of a Unique Marek's Disease Virus Gene Which Encodes a 38kD Phosphoprotein and is Expressed in both Lytcally Infected Cells and Latently Infected Lymphoblastoid Tumor Cells," Journal of Virology, 66:1:85-94, Jan. 1992.
Z. Cui et al., "Marek's Disease Virus Gene Clones Encoding Virus-Specific Phosphorylated Polypeptides and Serological Characterization of Fusion Proteins,"Virus Genes, 3:4:309-322, 1990, The Netherlands.
Z. Cui et al., "Structural Analysis and Transcriptional Mapping of the Marek's Disease Virus Gene Encoding pp38, an Antigen Associated with Transformed Cells" Journal of Virology, 65:12:6509-6515, Dec. 1991, USA.
I. Sithole et al., "Synthesis and Processing of the Marek's Disease Herpes-virus B Antigen Glycoprotein Complex," Journal of Virology, 62:11:4270-4279 Nov. 1988.
Claessens Johannes Antonius Joseph
Morgan Robin Wilson
Sondermeijer Paulus Jacobus Antonius
Akzo Nobel N.V.
Blackstone William M.
Guzo David
Muir Gregory R.
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