Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant virus encoding one or more heterologous proteins...
Patent
1990-11-09
1999-02-02
Railey, II, Johnny F.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant virus encoding one or more heterologous proteins...
424 932, 4351723, 4353201, C12N 1564, C12N 1586, A61K 3912
Patent
active
058661360
ABSTRACT:
A recombinant vaccine comprises a vaccine vector which incorporates a first nucleotide sequence capable of being expressed as all or a part of an antigenic polypeptide, together with a second nucleotide sequence capable of being expressed as all or a part of a lymphokine effective in enhancing the immune response to the antigenic polypeptide. The vaccine vectors include poxvirus, herpes virus or adenovirus, and the lymphokine may be an interleukin, tumour necrosis factor or gamma-interferon. The vaccine vector may express an antigenic polypeptide which is foreign to the host vector.
REFERENCES:
patent: 4631191 (1986-12-01), Dale et al.
J.-P. Van Eendenburg et al., AIDS Res. and Hum. Retrovir. 5(1):41-50 (1989).
Leong et al., "Generation of Enhanced Immune Responses by Consecutive Immunzation with DNA and Recombinant Fowl Pox Vectors," In: Vaccines 95, Cold Spring Harbor Press, 1995, pp. 327-331.
Dinarello, Adv. Immunopharmacol., 3, Proc. Int. Conf. 3rd., 1985 (publ. 1986), pp. 223-230.
Bektemirov et al., Chemical Abstracts, 92, No. 19, May 12, 1980, p. 446, Abstract No. 162033q.
Yokota et al., Proc. Natl. Acad. Sci. USA, 83, No. 16, Aug., 1986, pp. 5894-5898.
Hu et al., Nature, 320, Apr. 1986, pp. 537-540.
Cremer, The Yearbook of Agriculture, U.S. Dept. of Agriculture, 1986, pp. 104-104.
B.D. Davis et al, Eds. Microbiology, Hagerstown: Harper and Row; 1980, p. 294.
S.L. Hu et al. (1983) Nature 302:490-495.
Animal Pharm. (1986) Mar. 14, vol. 100, p. 19. (Abstract).
Andrew Marion Elizabeth
Boyle David Bernard
Coupar Barbara Elizabeth Howieson
Ramshaw Ian Allister
Commonwealth Scientific and Industrial Organisation
Railey II Johnny F.
The Australian National University
LandOfFree
Recombinant vaccine does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Recombinant vaccine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant vaccine will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1114677