Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...
Patent
1995-06-07
1999-02-02
Degen, Nancy
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Amino acid sequence disclosed in whole or in part; or...
4241881, 4241991, 4353201, A61K 3912
Patent
active
058661310
ABSTRACT:
A recombinant vaccine comprises a vaccine vector which incorporates a first nucleotide sequence capable of being expressed as all or a part of an antigenic polypeptide, together with a second nucleotide sequence capable of being expressed as all or a part of a lymphokine effective in enhancing the immune response to the antigenic polypeptide. The vaccine vectors include poxvirus, herpes virus or adenovirus, and the lymphokine may be an interleukin, tumour necrosis factor or gamma-interferon. The vaccine vector may express an antigenic polypeptide which is foreign to the host vector.
REFERENCES:
patent: 4631191 (1986-12-01), Dale et al.
Animal Pharm. 100:19 Mar. 1986.
Hu et al. Apr. 1986 Nature 320(10) 537-540.
Barinaga, M. 1994 Science vol. 266 p. 1326.
Marshall, E. 1995 Science vol. 269 pp. 1050-1055.
Crystal, R. 1995 Science vol. 270, pp. 404-410.
Jolly, D. 1994 Cancer Gene Therapy vol. 1(1) pp. 51-64.
Orkin, S.H. et al. 1995(Dec.) Report and Recommendations of the Panel to Assess the NIH Investment in Research on Gene Therapy. NIH Reports.
van Edenberg, Jun. 1989 AIDS Research and Human Retroviruses vol. 5(1) pp. 41-50.
Faney, J.L. et al. 1992 Clin. Exp. Immunol. vol. 88 pp. 1-5.
Johnson, M.I. et al 1993 Science vol. 260 pp. 1286-1293.
Animal Pharm., 100:19, Mar. 1986.
Hu et al, "Expression of AIDS virus envelope gene in recombinant vaccinia viruses", Nature 320(10):537-540, Apr. 1986.
Andrew Marion Elizabeth
Boyle David Bernard
Coupar Barbara Elizabeth Howieson
Ramshaw Ian Allister
Commonwealth Scientific and Industrial Research Organisation
Degen Nancy
The Australian National University
Yucel Irem
LandOfFree
Recombinant vaccine does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Recombinant vaccine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant vaccine will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1114633