Recombinant trichosanthin and coding sequence

Details Recombinant trichosanthin and coding sequence Recombinant trichosanthin and coding sequence

1989-09-07

1992-03-31

Rollins, John W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 28, 4353201, 435849, C07H 1700, C12N 1500

Patent

active

051010259

ABSTRACT:
Disclosed are the entire coding sequence for unprocessed and mature trichosanthin from Trichosanthes kirilowii, and primers derived from this coding sequence for use in obtaining the coding sequences of ribosome inactivating proteins which have regions of amino acid sequence identical to those of trichosanthin. Also disclosed is a recombinant trichosanthin protein produced from the coding sequence, and the mature protein with amino-terminal and/or carboxy-terminal extensions.

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