Recombinant trichosanthin and coding sequence

Details Recombinant trichosanthin and coding sequence Recombinant trichosanthin and coding sequence

1991-12-09

1992-11-24

Rollins, John W.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4351723, C12P 2106, C12N 1500

Patent

active

051660563

ABSTRACT:
Disclosed are the entire coding sequence for unprocessed and mature trichosanthin from Trichosanthes kirilowii, and primers derived from this coding sequence for use in obtaining the coding sequences of ribosome inactivating proteins which have regions of amino acid sequence identical to those of trichosanthin. Also disclosed is a recombinant trichosanthin protein produced from the coding sequence, and the mature protein with amino-terminal and/or carboxy-terminal extensions.

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