Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1991-11-07
1997-11-18
Tsang, Cecilia J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530327, 530328, 530329, 530330, 530331, 514 14, 514 15, 514 16, 514 17, 514 18, A61K 3600, C07K 706, C07K 708, C07K 710
Patent
active
056887680
ABSTRACT:
The DNA encoding the cell surface receptor for thrombin has been cloned and sequenced. The availability of this DNA permits the recombinant production of thrombin receptor which can be produced at cell surfaces and is useful in assay systems both for the detection of thrombin and for the evaluation of candidate thrombin agonists and antagonists. Further, the elucidation of the structure of the thrombin receptor permits the design of agonist and antagonist compounds which are useful diagnostically and therapeutically. The availability of the thrombin receptor also permits production of antibodies specifically immunoreactive with the receptor per se or with specific regions thereof which are also useful diagnostically or therapeutically.
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Coughlin Shaun R.
Scarborough Robert M.
COR Therapeutics Inc.
Marshall S. G.
Tsang Cecilia J.
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