Recombinant techniques for production of human brain natriuretic

Details Recombinant techniques for production of human brain natriuretic Recombinant techniques for production of human brain natriuretic

1990-02-08

1997-10-07

LeGuyader, John L.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4351723, 4352401, 4352402, 43525233, 4353201, 536 2351, C12N 1516, C12N 1585

Patent

active

056747101

ABSTRACT:
The cDNA sequence encoding porcine brain natriuretic peptide and related genes encoding canine and human peptides with natriuretic activity are disclosed. The gene is shown to make accessible the DNAs encoding analogous natriuretic peptides in other vertebrate species. The genes encoding these NPs can be used to effect modifications of the sequence to produce alternate forms of the NPs and to provide practical amounts of these proteins. The NPs of the invention can also be synthesized chemically.

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