Recombinant protein production in a human cell

Details Recombinant protein production in a human cell Recombinant protein production in a human cell

2005-02-15

2005-02-15

Wax, Robert A. (Department: 1653)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C435S069100, C435S320100, C435S455000, C435S069700, C536S023100, C536S023500, C536S023720, C536S024100

Reexamination Certificate

active

06855544

ABSTRACT:
Methods and compositions for the production of recombinant proteins in a human cell line. The methods and positions are particularly useful for generating stable expression of human recombinant proteins of interest that are modified post-translationally, for example, by glycosylation. Such proteins may have advantageous properties in comparison with their counterparts produced in non-human systems such as Chinese Hamster Ovary cells.

REFERENCES:
patent: 5994128 (1999-11-01), Fallaux et al.
patent: 6653101 (2003-11-01), Cockett et al.
patent: WO 9303163 (1993-02-01), None
patent: WO 9529994 (1995-11-01), None
patent: WO 9700326 (1997-01-01), None
Setoguchi et al. “Stimulation of Erythropoiesis by in vivo gene therapy: Physiologic consequences of transfer of the humanerythropietin gene to experimental animals using an adenovirus vector,” Blood, vol. 84 (9), Nov. 1, 1994, pp 2946-2953.*
Ghosh-Choudhury et al., Protein IX, a minor component of the human adenovirus capsid, is essential for the packaging of the full length genomes. The EMBO Journal, 1987, pp. 1733-1739, vol. 6, No. 6.
Louis et al., Cloning and Sequencing of the Cellular—Viral Junctions from the Human Adenovirus Type 5 Transformed 293 Cell Line, Virology, 1997, pp 423-429, vol. 233.
NCBI Entrez Nucleotide accession No. U38242.
NCBI Entrez Nucleotide accession No. NC 002018.
NCBI Entrez Nucleotide accession No. X02996 J01967 J01968 J01970 J01971 J01972 J01974 J01976 J01977 J01978 J01979 K00515 V00025 V00026 V00027 V00029.
PCT International Search Report. PCTN1.00 00247. dated Oct. 9, 2000. 3 pages.

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