Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1996-09-09
1998-09-08
Hendricks, Keith D.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435325, 435419, 4352523, 4352542, 536 235, 530350, 530333, 530351, 530381, 935 9, 935 49, C07K 100, C12P 2106, C07H 2104
Patent
active
058044175
ABSTRACT:
The invention lies in the field of genetic engineering and, in particular, is concerned with the use of 7B2 as chaperone in vivo or in vitro. The invention accordingly concerns a method for producing a desired protein in vivo with the aid of recombinant cells capable of expressing 7B2 and of expressing and secreting said desired protein. Another aspect is accordingly an in vitro method for the deaggregation or prevention of aggregation of protein by treating the protein with 7B2.
REFERENCES:
Biochem. Biophys. Res. Commun., 174, 586-592 (1991).
John S. Kizer et al.
Von Heijne, G., in Nucleic Acids Res. 14, 4683 (1986).
Hinnen et al., Proc. Natl. Acad. Sci. USA, 75, 1929 (1978).
Inagnostopoulos et al., J. Bacteriol. 81, 741 (1961).
M. Mandel et al., J. Mol. Biol. 53, 159 (1970).
Van Daijnkoven, et al., J. Immunol. Methods, 142, 187-198 (1991).
Martens, FEBS Letts., 234, 160-164 (1988).
Haendler, et al., Gene 83, 39-46 (1989).
Rothblatt et al., EMBO J., 6, 3455-3463 (1982).
Klebe et al., Gene 25, 333-341 (1983).
Barr et al., J. Biol. Chem. 263, 16471-16478 (1988).
Steube, K. et al., Eur. J. Biochem., 198, 651-657 (1991).
Belt et al., Gene 84, 407-417 (1989).
Ayoubi et al., Cell Tissue Res. 264, 329-334 (1991).
Gatenby et al., Trends in Biotechnology 8, 354-358 (1990).
Chaudhuri Bhabatosh
Martens Gerardus Julianus Maria
Stephan Christine
Hendricks Keith D.
Novartis Corporation
Nowak Henry P.
LandOfFree
Recombinant production of proteins using 7B2 protein does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Recombinant production of proteins using 7B2 protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant production of proteins using 7B2 protein will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1281196