Recombinant production of novel polyketides

Details Recombinant production of novel polyketides Recombinant production of novel polyketides

2007-12-25

2007-12-25

Nashed, Nashaat T. (Department: 1656)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

C435S132000, C435S252300

Reexamination Certificate

active

11227404

ABSTRACT:
Novel polyketides and novel methods of efficiently producing both new and known polyketides, using recombinant technology, are disclosed. In particular, a novel host-vector system is described which is used to produce polyketide synthases which in turn catalyze the production of a variety of polyketides.

REFERENCES:
patent: 4935340 (1990-06-01), Baltz et al.
patent: 5672491 (1997-09-01), Khosla et al.
patent: 5824513 (1998-10-01), Katz et al.
patent: 5830750 (1998-11-01), Khosla et al.
patent: 5962290 (1999-10-01), Khosla et al.
patent: 6004787 (1999-12-01), Katz et al.
patent: 6022731 (2000-02-01), Khosla et al.
patent: 6060234 (2000-05-01), Katz et al.
patent: 6063561 (2000-05-01), Katz et al.
patent: 6200813 (2001-03-01), Katz et al.
patent: 6271255 (2001-08-01), Leadlay et al.
patent: 6399382 (2002-06-01), Khosla et al.
patent: 0 092 388 (1983-10-01), None
patent: WO-93/13663 (1993-07-01), None
patent: WO-95/08548 (1995-03-01), None
patent: WO-98/51695 (1998-11-01), None
Beck et al., Eur. J. Biochem. (1990) 192:487-498.
Chater, Bio/Technology (1990) 8:115-121.
Cortes et al., Nature (1990) 348:176-178.
Davis et al., Abst. of the Genetics of Industrial Microorganisms Mtg. (1994) P288:192.
Donadio et al., Industrial Microorganisms: Basic and Applied Molecular Genetics, Baltz et al. (eds.) Chapter 31, pp. 257-265 (1993).
European Search Report for EP 05 00 7590, mailed on Oct. 18, 2005, 9 pages.
Floss, Tetrahydron (1991) 47(31):6045-6058.
Fu, Biochemistry (1994) 33(31):9321-9326.
Hopwood and Sherman, Annu. Rev. Genet. (1990) 24:37-66.
Hutchinson, Bio/Technology (1994) 12:375-380.
Malpartida et al., Nature (1984) 309:462-464.
McAlpine et al., Journal of Antibiotics (1987) 40(8):1115-1122.
McDaniel et al., Science (1993) 262:1546-1550.
Pfeifer and Khosla, Microbiology and Molecular Biology Reviews (2001) 65:106-118.
Reeves et al., Chemistry & Biology (2004) 11:1465-1472.
Rodriguez et al., Applied genetics and Molecular Biotechnology (2004) 66:85-91.
Rohr, Angew. Chem. Int. Ed. Engl. (1995) 34(8):881-885.
Strohl et al., J. Ind. Microbiol. (1991) 7:163-174.
Tsoi et al., Chem. Biol. (1995) 2(6):355-362.
Tuan et al., Gene (1990) 90:21-29.
European Search Report for EP 05021915.3, mailed on Nov. 24, 2005, 5 pages.
Fu et al., Chemistry & Biology (1994) 1:205-210.
Kao et al., Science (1994) 265:509-512.
McDaniel et al., Journal of the American Chemical Society (1993) 115:11671-11675.
McDaniel et al., Journal of the American Chemical Society (1995) 117:6805-6810.
McDaniel et al., Nature (1995) 375:549-554.
McDaniel et al., Proc. Natl. Acad. Sci. USA (1994) 91:11542-11546.
Donadio et al., PNAS USA (1993) 90:7119-7123.
Richardson et al., Journal of Bacteriology (1990) 172(7):3790-3798.
Bartel et al., J. Bacteriol. (1990) 172(9):4816-4826.
Bibb et al., EMBO J (1989) 8(9):2727-2735.
Caballero et al., Mol. Gen. Genet. (1991) 230:401-412.
Donadio et al., Science (1991) 252:675-679.
Donadio et al., Gene (1992) 115:97-103.
Fernandez-Moreno et al., Cell (1991) 66:769-780.
Fernandez-Moreno et al., J. Biol. Chem. (1992) 267:19278-19290.
Hallam, Gene (1988) 74:305-320.
Hershberger et al., Am. Soc. for Microbiol. (1989) (Washington, D.C.) pp. 68-84.
Hopwood et al., Phil. Trans. R. Soc. Lond. (1989) B324:549-562.
Hopwood et al., Nature (1985) 314 (6012):642-644.
Hutchinson, Ann Review Microbiol. (1993) 47:875912.
Katz et al., Ann. Review Microbiol. (1993) 47:875-912.
Khosla et al., Mole. Microbiol. (1992) 6(21):3237-3249.
Khosla et al., J. Bacteriol. (1993) 175:2197-2204.
MacNeil, Gene (1992) 115:119-125.
Malpartida et al., Mol. Gen. Genet. (1986) 205:66-73.
Roberts et al., Biochem. Soc. Trans. (1992) 21:325.
Roberts et al., Eur. J. Biochem. (1993) 214:305-311.
Robinson, Phil. Trans. R. Soc. Land B. (1991) 332:107-114.
Sherman et al., EMBO J (1989) 8:2717-2725.
Sherman et al., J. Bacteriol. (1992) 174:6184-6190.
Strohl et al., Molecular Microbiology (1992) 6(2):147-152.
Tsol et al., Database Caplus on STN, Chemical Abstract No. 123:169385.
Ziermann and Betlach, Biotechniques (1999) 26:106-110.

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